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Advisory Board

John J. Partridge, Ph.D., MRSC

Dr Partridge got his B. S., Prof. Chemistry from Wheaton College in 1964. He completed his Ph.D. in Organic Chemistry from Northwestern University in 1968. From 1968-1969, he was a Postdoctoral Fellow in Synthetic Organic Chemistry at Columbia University.

Dr Partridge started in the Department of Natural Products Chemistry at Hoffmann-LaRoche from 1969-1985. From 1985-1988, he worked in the Department of Synthesis Research at Hoffmann-LaRoche. He was the Head of Chemical Development Department at Glaxo Research Institute from 1988-1995. Dr. Partridge served as a Senior Research Advisor in the Chemical Development Department at GlaxoWellcome for five years, until 2000. From 2001 to the Present, Dr. Partridge worked in the Chemical Development Department at GlaxoSmithKline, and also worked as an independant consultant.

Dr Partridge brings a variety of expertise to Conformia, including Strategic Vision, Pharma Industry Contacts, Drug Discovery & Drug Development, Intellectual Property, Knowledge of cGMP & FDA Filings, Cost of Goods Analysis, In-Licensing, Laboratory & Pilot Plant Construction, Scientific Writing, Safety & Risk Management, and Litigation.

Honors and Awards

2001: Elected Member of the Royal Society of Chemistry (MRSC)
1995-97, 2001-02: Board of Visitors, North Carolina State University, Raleigh, NC
1989-95, 1998-01: Adjunct Professor of Chemistry, University of North Carolina, Chapel Hill, NC
1992: Elected Fellow of the American Association for the Advancement of Science (AAAS)
1985: Chair, Gordon Research Conference on Natural Products Chemistry, New Hampton, NH
1984: Adjunct Professor of Chemistry, Seton Hall University, South Orange, NJ

Recent Publications, Patents and Lectures

"Pyridinium Salts, Compounds and Methods of Use", Klein, R. B., Selph, J. L., Partridge, J. J. and Reinhard, J. F., PCT Appl. WO 2004/078136 A2 (filed March 2, 2004; publ. September 16, 2004).

"Pyridyl Substituted Heterocycles Useful for Treating or Preventing HCV Infection", Singh, R., Goff, D. and Partridge, J. J., PCT Appl. US 2004/0127497 A1 (filed August 22, 2003; publ. July 1, 2004); PCT Appl. WO 2004/018463 A2 (filed August 22, 2003; publ. March 4, 2004).

"Pharmaceutically Active Morpholinol", Partridge J. J., US Patent 6,734,213 (May 11, 2004); Morgan, P. F., Musso, D. L. and Partridge J. J., US Patent 6,391,875 (May 21, 2002); US Patent 6,274,579 (August 14, 2001). USAN - RADAFAXINE HCl

"Refractive Index Probe Apparatus and System", Barger, L. A., Partridge, J. J., Walker, D. S. and Smith, R., PCT Appl. WO 03/032020 (filed October 3, 2002; publ. April 17, 2003).

"Synthesis of Fluticasone Derivatives", Partridge, J. J. and Walker, D. S., PCT Appl. WO 03/013427 (publ. February 20, 2003).

"Near Infrared Spectrum Measurement of Gases", Anderson, J. E., Purdy, K. A., Partridge J. J. and Walker, D. S., PCT Int. Appl. WO00/45155 (published August 3, 2000).

"Preparation of Chiral Drug Substances: Use of Synthetic Organic Chemistry and Related Technologies", Founders Day Chemistry Lecture, University of Virginia, Charlottesville, VA (2000).

"Enantioselective Synthesis: The Optimum Solution", Partridge, J. J. and Bray, B. L. in Process Chemistry in the Pharmaceutical Industry, (Gadamasetti, K. G., Ed.) Marcel Dekker, New York, NY, 1999, pp. 310-325.

"Convergent Catalytic Asymmetric Synthesis of Camptothecin Analog GI147211C", Fang, F. G., Partridge, J. J., Sharp, M. J. and Xie, S., et al, Tetrahedron, 1997, 53, 10953-10970.

"The Synthesis of Enantiomerically Pure Nucleosides", Bray, B. L., Goodyear, M. D., Partridge, J. J. and Tapolczay, D. J. in Chirality in Industry II, (Collins, A. N., Sheldrake, G. N. and Crosby, J., Ed.) John Wiley and Sons, UK, 1997, pp 41-78.

"Discovery consists of seeing what everybody has seen and thinking what nobody has thought" ­ Albert Szent-Gyorgyi

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